Key Finding In Stem Cell Self-Renewal

A University of Minnesota-led research team has proposed a mechanism for the control of whether embryonic stem cells continue to proliferate and stay stem cells, or differentiate into adult cells like brain, liver or skin. The work has implications in two areas. In cancer treatment, it is desirable to inhibit cell proliferation…
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Directing Stem Cells To Increase Bone Formation And Bone Strength

A research team led by UC Davis Health System scientists has developed a novel technique to enhance bone growth by using a molecule which, when injected into the bloodstream, directs the body’s stem cells to travel to the surface of bones…
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Stanford Scientists Turn Skin Cells Into Neural Precusors, Bypassing Stem-Cell Stage

Mouse skin cells can be converted directly into cells that become the three main parts of the nervous system, according to researchers at the Stanford University School of Medicine. The finding is an extension of a previous study by the same group showing that mouse and human skin cells can be directly converted into […]

Improved Understanding Of The Thalamus Offers Potential Stroke Therapy

The thalamus is the central translator in the brain: Specialized nerve cells (neurons) receive information from the sensory organs, process it, and transmit it deep into the brain. Researchers from the Institute of Toxicology and Genetics (ITG) of KIT have now identified the genetic factors Lhx2 and Lhx9 responsible for the development of these neurons…
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New Process Could Advance Use Of Healthy Cells Or Stem Cells To Treat Disease

In a discovery that may help speed use of “cell therapy” - with normal cells or stem cells infused into the body to treat disease - scientists are reporting development of a way to deliver therapeutic human cells to diseased areas within the body using a simple magnetic effect. Their report appears in ACS’ […]

Stanford Study Finds IPS Cells Match Embryonic Stem Cells In Modeling Human Disease

Stanford University School of Medicine investigators have shown that iPS cells, viewed as a possible alternative to human embryonic stem cells, can mirror the defining defects of a genetic condition - in this instance, Marfan syndrome - as well as embryonic stem cells can. An immediate implication is that iPS cells could be used to […]

Bone Marrow-Derived Cells Differentiate In The Brain Through Mechanisms Of Plasticity

Bone marrow-derived stem cells (BMDCs) have been recognized as a source for transplantation because they can contribute to different cell populations in a variety of organs under both normal and pathological conditions…
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Therapy Improves Stem Cell Engraftment In Umbilical Cord Blood Transplant Recipients

A therapy involving a natural compound may improve the ability of stem cells from umbilical cord blood to engraft in patients receiving a stem cell transplant for cancer or other diseases, a phase I clinical trial led by Dana-Farber Cancer Institute scientists indicates…
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First Animal Product-Free Clinical Grade Human Embryonic Stem Cell Lines Intended For Public Benefit Produced In UK

Stem cell scientists at King’s College London have announced that they have submitted to the UK Stem Cell Bank (UKSCB) their first clinical grade human embryonic stem (hES) cell lines that are free from animal-derived products, known as ‘xeno-free’ stem cells…
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Newly Discovered Heart Stem Cells Make Muscle And Bone

Researchers have identified a new and relatively abundant pool of stem cells in the heart. The findings in the December issue of Cell Stem Cell, a Cell Press publication, show that these heart cells have the capacity for long-term expansion and can form a variety of cell types, including muscle, bone, neural and heart […]


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