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Sepracor Inc. (Nasdaq: SEPR) announced the presentation of LUNESTA ® brand eszopiclone Phase IV study data at the 21st European College of Neuropsychopharmacology (ECNP) Congress in Barcelona. The poster presentations reflected results from a 12-week, double-blind, randomized safety and efficacy study of 388 elderly patients (65-85 years of age) who were administered either LUNESTA 2 mg or placebo nightly.

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Researchers at The Wistar Institute have deciphered the structure of the active region of telomerase, an enzyme that plays a major role in the development of nearly all human cancers. The landmark achievement opens the door to the creation of new, broadly effective cancer drugs, as well as anti-aging therapies. Researchers have attempted for more than a decade to find drugs that shut down telomerase widely considered the No.

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A study in the Sept. 1 issue of the journal Sleep shows that the subjective interpretation of temperature change is decreased in older adults, particularly those who suffer from insomnia. The study is the first to find pronounced attenuation of subjective thermosensitivity in elderly insomniacs within the small range of normal bed temperatures.

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Hutchinson-Gilford progeria syndrome (HGPS) is a rare childhood disease that resembles premature aging, and few affected children reach their teenage years. It is caused by a mutation in the LMNA gene that leads to the formation of progerin - a mutant form of the protein prelamin A. Once made, both progerin and normal prelamin A have the molecule farnesyl attached to them. This addition is later removed from normal prelamin A, whereas it cannot be removed from progerin.

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Age may not be rust after all. Specific genetic instructions drive aging in worms, report researchers at the Stanford University School of Medicine. Their discovery contradicts the prevailing theory that aging is a buildup of tissue damage akin to rust, and implies science might eventually halt or even reverse the ravages of age. “We were really surprised,” said Stuart Kim, PhD, professor of developmental biology and of genetics, who is the senior author of the research.

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Starting an exercise routine is no easy task - it is even harder to stick with one. This is the focus of a new study on the “Step and Stride with Ruby” walking program released today by AARP and the Red Hat Society with support from the AARP Foundation’s Women’s Leadership Circle. Over 500 women in Red Hat Society Chapters participated in the study, which found that friendly competition and participation in group activities was the key to sticking with an exercise regimen.

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University of Queensland research is showing the benefits of resistance training in keeping older Australians in tip top form. Dr Tim Henwood, a postdoctoral research fellow with UQ and Blue Care, said his recently completed PhD research investigated how people over the age of 65 responded to resistance training. “What we were looking at was how simple resistance training can improve muscle strength, power and functional performance.” Dr Henwood said.

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General Motors will contract with benefits consultant firm Extend Health to provide guidance to retirees in choosing appropriate Medicare plans to replace benefits previously offered by GM, the Detroit Free Press reports. The automaker on Tuesday

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Bringing a community nursing and physiotherapy team into residential care homes for older people improves quality of life and reduces hospital admissions, according to a new evaluation study’s reports published by the Joseph Rowntree Foundation.

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Diet can strongly influence how long you live and your reproductive success, but now scientists have discovered that what works for males can be very different for females. In the first study of its kind, the researchers have shown that gender plays a major role in determining which diet is better suited to promoting longer life or better reproductive success.

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