Grafting Of Human Spinal Stem Cells Into ALS Rats Best With Immunosuppressant Combination

A team of researchers grafting human spinal stem cells into rats modeled with amyotrophic lateral sclerosis (ALS), also known as “Lou Gehrig’s Disease,” a degenerative, lethal, neuromuscular disease, have tested four different immunosuppressive protocols aimed at determining which regimen improved long-term therapeutic effects…
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Hope For Muscle Wasting Disease

A health supplement used by bodybuilders could be the key to treating a life-threatening muscular dystrophy affecting hundreds of Australian children, new research shows…
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Discovery Helps Explain Progression Of Lou Gehrig’s Disease, Offers New Therapy Approach

Researchers in Uruguay and Oregon have discovered a previously unknown type of neural cell that appears to be closely linked to the progression of amytrophic lateral sclerosis, or Lou Gehrig’s disease, that they believe will provide an important new approach to therapies…
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New Insight Into Fatal Spinal Disease Could Lead To Treatments For Muscular Dystrophy And ALS

Researchers at the University of Missouri have identified a communication breakdown between nerves and muscles in mice that may provide new insight into the debilitating and fatal human disease known as spinal muscular atrophy (SMA). “Critical communication occurs at the point where nerves and muscles ‘talk’ to each other…
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Crucial Link Between Prions And ALS Discovered - May Transform Treatment

A group of investigators from the University of British Columbia and the Vancouver Coastal Health Research Institute have discovered a crucial link between prions and the neurodegenerative disease ALS (Amyotrophic Lateral Sclerosis), also known as Lou Gehrig’s disease. This finding is considerable as it paves the way to new approaches to the treatment of […]

New Class Of Stem Cell-Like Cells Discovered In Spinal Cord Offers Possibilities For Spinal Cord Repair

The Allen Institute for Brain Science announced today the discovery of a new class of cells in the spinal cord that act like neural stem cells, offering a fresh avenue in the search for therapies to treat spinal cord injury and disease…
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Common Cause Of All ALS Forms Identified - Seen As A Major ALS Breakthrough

All forms of ALS are caused by a protein recycling system in the neurons of the spinal cord and brain that breaks down. For neurons to function properly, they rely on the effective recycling of the protein building blocks in cells - they need to be removed and reprocessed. In ALS, when the recycling system […]

New Model Of ALS Is Based On Human Cells From Autopsied Tissue

By isolating cells from patients’ spinal tissue within a few days after death, researchers funded by the National Institutes of Health have developed a new model of the paralyzing disease amyotrophic lateral sclerosis (ALS). They found that during the disease, cells called astrocytes become toxic to nerve cells - a result previously found in […]

SIGMAR1 Gene Mutation Linked To Juvenile ALS Development, Researchers Identify

From the Kingdom of Saudi Arabia, investigators have identified a mutation on the SIGMAR1 gene linked with the development of juvenile amyotrophic lateral sclerosis (ALS)…
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Human-Cell-Derived Model Of ALS Provides A New Way To Study The Majority Of Cases

For decades, scientists have studied a laboratory mouse model that develops signs of the paralyzing disease amyotrophic lateral sclerosis (ALS) as they age. In a new study appearing in Nature Biotechnology, investigators at Nationwide Children’s Hospital have developed a new model of ALS, one that mimics sporadic ALS, which represents about 90 percent of all […]


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