MRSA: From A Nosocomial Pathogen To An Omnipresent Source Of Infection

In German hospitals, each year 132 000 patients contract infection with methicillin-resistant Staphylococcus aureus (MRSA). For more than a decade, different countries have reported an increasing incidence of MRSA infections in the general population (”community associated” [CA-] MRSA)…
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Drug-Resistant Bacteria Defeated By New Compound

Chemists at Brown University have synthesized a new compound that makes drug-resistant bacteria susceptible again to antibiotics. The compound - BU-005 - blocks pumps that a bacterium employs to expel an antibacterial agent called chloramphenicol. The team used a new and highly efficient method for the synthesis of BU-005 and other C-capped dipeptides…
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Stopping “Superbugs” In Their Tracks

University of Virginia Health System researchers are the first in the world to develop a new and faster method to track major infection-causing “superbugs” a major key in preventing the spread of deadly infections. Their research, published in the November/December 2011 issue of the online journal mBio, comes at a critical time…
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New TB Treatment Limits Infection While Reducing Drug Resistance

It’s estimated that nearly one-third of the world’s population - more than two billion people - are infected with Mycobacterium tuberculosis. According to the World Health Organization, 5 to 10 percent of infected people eventually develop active tuberculosis and can transmit the bacterium to others. Almost two million die from the disease each year…
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Novel Index For Tracking Drug Resistance - Drug Resistance Index

Ramanan Laxminarayan, Director of Extending the Cure, and Keith P. Klugman, Professor of Global Health at Emory University describe a novel index for tracking resistance in a report published in this week’s British Medical Journal Open…
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MDR-AB Bacteria Found In 48% Of All Patient Rooms

A new study has revealed that Multidrug-resistant Acinetobacter baumannii (MDR-AB) was found in almost half (48%) of patients rooms who were infected or colonized with the germ. The report is published in the November issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and […]

Different Paths To Drug Resistance In Leishmania

Two remarkable discoveries were revealed by researchers into genome analysis of Leishmania parasites. These results uncovered a surprising level of variation at the genome structure level. First, they found that the DNA sequence of individual strains of each species populations is almost completely identical…
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Compound Disables Bacteria Instead Of Killing Them

After 70 years, antibiotics are still the primary treatment for halting the spread of bacterial infections. But the prevalence of antibiotic resistance is now outpacing the rate of new drug discovery and approval…
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Surgeons Develop A Faster, Less Expensive Technique To Identify Bacterial Infections And Determine Antibiotic Resistance

Surgeons at Detroit Medical Center and Wayne State University in Detroit are developing a faster, less expensive method of identifying bacterial infections and determining their antibiotic resistance…
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Mapping MRSA’s Family Tree

Check into a hospital and you run the risk of infection with a methicillin-resistant strain of the bacterium Staphylococcus aureus, or MRSA. But present day MRSA might have been worse if it had descended directly from a 1950s version of the bug, according to a study co-authored by Barry N…
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