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Archive for the 'Genetics' Category

St. Jude Identifies Genomic Causes Of A Certain Type Of Leukemia Relapse

Dec 2nd 2008Drug InformationGenetics

Scientists at St. Jude Children’s Research Hospital have identified distinctive genetic changes in the cancer cells of children with acute lymphoblastic leukemia (ALL) that cause relapse. The finding offers a pathway to designing treatments for ALL relapse in children and, ultimately, in adults. The most common childhood cancer, ALL affects thousands of children annually in the United States.

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Study Identifies Genetic Variants Giving Rise To Differences In Metabolism

Dec 2nd 2008Drug InformationGenetics

Common genetic polymorphisms induce major differentiations in the metabolic make-up of the human population, according to a paper published November 28 in the open-access journal PLoS Genetics. An international team of researchers, led by Karsten Suhre, has conducted a genome-wide association study with metabolomics, identifying genetic variants in genes involved in the breakdown of fats.

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Insights Into Process Of Malarial Drug Resistance

Dec 2nd 2008Drug InformationGenetics

Malaria, one of the oldest diseases known to man, has shown no signs of slowing down as it ages. More than 1 million children die from malaria in sub-Saharan Africa each year, and in areas along the Thailand/Cambodian border multiple drug-resistant strains of the disease are becoming commonplace.

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