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University of Iowa researchers and collaborators have identified new genetic mutations that likely cause the common form of cleft lip and palate.The results could eventually help clinicians predict a family’s risk of having more children with the condition. The findings appear in the online Early Edition of the Proceedings of the National Academy of Sciences. [click link for full article]

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A global research network is needed if scientists are ever going to understand and prevent cleft palate, say experts at the first World Health Organization Collaborating Centre set up to develop such a structure. [click link for full article]

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A new study finds that women who take folic acid supplements early in their pregnancy can substantially reduce their baby’s chances of being born with a facial cleft.Researchers at the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health, found that 0.4 milligrams (mg) a day of folic acid reduced by one third the baby’s risk of isolated cleft lip (with or without cleft palate). [click link for full article]

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Pioneering research that could lead to a breakthrough in understanding the causes of cleft palate in newborn babies has begun in Manchester, UK. Dr Jill Dixon, in The University of Manchester’s School of Dentistry, has been awarded a three-year New Investigator Award by the Medical Research Council to look into the distressing birth defect. [click link for full article]

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