Hidden Side Of Prion Diseases Discovered By Medical Researchers In Canada And The US

Medical researchers in Canada and the United States recently published their joint findings that fatal prion diseases, which include BSE or “mad cow disease,” have a hidden signature…
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Cellular Stress Can Induce Yeast To Promote Prion Formation

It’s a chicken and egg question. Where do the infectious protein particles called prions come from? Essentially clumps of misfolded proteins, prions cause neurodegenerative disorders, such as mad cow/Creutzfeld-Jakob disease, in humans and animals. Prions trigger the misfolding and aggregation of their properly folded protein counterparts, but they usually need some kind of “seed” to […]

Tracking Down BSE And Creutzfeldt-Jakob Disease

Prion diseases such as Creutzfeldt-Jakob disease in humans and bovine spongiform encephalopathy (BSE) in cattle are transmissible neurodegenerative diseases linked to the aggregation of the prion protein in the central nervous system. It is known that the aggregation of prion proteins promotes neuronal decay with fatal consequences for the infected individual…
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Rinderpest Is Dead; Second Disease In History Declared Eradicated

The Romans couldn’t beat it when they ruled the world, but today in Rome the UN has declared the eradication of rinderpest, the second disease in all of human history to be successfully wiped out after smallpox. Scientists are celebrating victory over a deadly animal disease that cattle herders around the world have dreaded for […]

When Coroners Said No To Post-Mortem Tissue Collection They Were Wrong, Academics Argue

The Coroner’s Society “failed” in its duty to protect public health by refusing to take part in vCJD study. The creation of a post-mortem tissue archive for a study of the human form of mad cow disease failed because of a “misguided” refusal by coroners to participate…
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Fast, Sensitive Blood Test For Human Prion Disease

WHAT: Scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), report that they have developed a method -10,000 times more sensitive than other methods - to detect variant Creutzfeldt-Jacob disease (vCJD) in blood plasma. vCJD is a type of prion disease in humans that leads […]

STERIS Pioneers Prion Decontamination Technologies

Following recent patient safety alerts, prion diseases - such as Creutzfeldt-Jakob disease (CJD) and variant CJD (vCJD) - are of increasing concern within the healthcare environment, as their causative agents can be extremely resistant to the cleaning, disinfection and sterilization methods currently used in many hospitals…
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Canadian Blood Services To Expand Deferral Policy For vCJD

Canadian Blood Services is expanding its deferral policy for vCJD (variant Creutzfeldt -Jakob disease) policy to include Saudi Arabia. A new question will be added to the Record of Donation donor questionnaire asking each donor if he or she has spent a cumulative total of six months or more in Saudi Arabia between 1980 and […]

New Research Focuses On Prion Diseases

New research by Chongsuk Ryou, researcher at the UK Sanders-Brown Center on Aging and professor of microbiology, immunology and molecular genetics in the UK College of Medicine, may shed light on possible treatments for prion diseases…
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Researchers Identify Biomarker For Creutzfeldt-Jakob Disease

Neena Singh, MD, PhD and colleagues at Case Western Reserve University School of Medicine have identified the first disease-specific biomarker for sporadic Creutzfeldt-Jakob disease (sCJD), a universally fatal, degenerative brain disease for which there is no cure. sCJD is one of the causes of dementia and typically leads to death within a year of disease […]


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