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Jul 16th 2008Drug InformationCancer
Study results could provide clue to origin of genome instability leading to cancers In the past 10 years, researchers in genome stability have observed that many kinds of cancers are associated with areas where human chromosomes break. More recently, scientists have discovered that slow or altered replication causes chromosomal breaking.
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Jul 16th 2008Drug InformationCancer
Three hard hitting films - designed by teenagers for teenagers - were launched after a national competition helped uncover the next generation of British film makers. Cancer Research UK and Channel 4’s 4Talent launched a joint initiative - funded by the Department of Health - called BREATHE to produce a selection of short online films to encourage young smokers to quit and deter others from starting.
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Jul 16th 2008Drug InformationCancer
Scientists of the Division of Theoretical Bioinformatics at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) in Heidelberg have simulated on the computer how cells decide whether or not to migrate. Using their results, the researchers were able to predict the molecular targets within a cell that have to be hit so that its behavior changes in a particular direction. This method may help to develop new treatments against cancer metastasis.
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Jul 16th 2008Drug InformationCancer
Brain cancer experts at the University of Alabama at Birmingham (UAB) have been selected for membership in the Ivy Genomics-Based Medicine Project. The project is a national consortium of cutting-edge hospitals and academic centers working to improve treatment and survival for patients with a kind of malignant brain tumor called a glioma. As part of the nine-member consortium, UAB will serve as the only research site in the Southeast.
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Jul 16th 2008Drug InformationCancer
A microchip-based device that detects and analyses tumour cells in the bloodstream proved effective in determining the genetic signature of lung tumours, allowing identification of patients appropriate for targeted treatment in a pilot study in patients with non-small-cell lung cancer (NSCLC).
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Jul 16th 2008Drug InformationCancer
Human cancer cells divide and conquer. Unless physicians can control that division with surgery, chemotherapy or radiation, the wildly dividing cells will eventually destroy a person’s life. Researchers have known for some time that an enzyme called telomerase is crucial to cancer’s progress.
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Jul 16th 2008Drug InformationCancer
Researchers from Weill Cornell Medical College have identified a type of cancer stem cell that might initiate metastatic cancer, which spreads beyond the original, primary tumor site and to other locations within the body. For the first time, scientists have revealed that the molecular profiles of these cancer stem cells are much different than those located in primary tumors. The study’s senior author Dr. Shahin Rafii — the Arthur B.
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Jul 16th 2008Drug InformationCancer
UroToday.com - A study by Dr. Uccini, et al., evaluated the molecular evidence of the independent origin of multiple Wilms tumors in a patient who has WAGR syndrome. The paper was a description of the procedure, technique and its results. They had one patient who was 1 year of age. This child developed two synchronous bilateral Wilms tumors that were resected by partial nephrectomy. Histologically, these tumors were fetal rhabdomyomatous nephroblastomas.
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Jul 16th 2008Drug InformationCancer
Prostate cancer cells cause disease in bones with the help of FGF9 Although prostate cancer is the second most common cause of death from cancer in the US, it is not the tumor in the prostate that usually causes death. Rather, death mainly occurs as a result of the tumor spreading to the bones, where it is known as an osteoblastic bone metastasis.
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Jul 16th 2008Drug InformationCancer
Researchers conducting a clinical trial of a dendritic cell vaccine designed to fight malignant brain tumors called glioblastoma multiforme (GBM) have found a correlation between the “intensity” of a patient’s immune response and clinical outcome, according to an article in the July 15 issue of the journalCancer Research.
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