Chaos In The Cell’s Command Center

A defective operating system is never a good thing. Like computers, our cells depend on operating systems to drive normal functions. Gene expression programs comprise the software code our cells rely on, with each cell type controlled by its own program. Corrupted programs can trigger disease…
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Device Provides A Platform For Viewing Cancer Cells And Other Macromolecules In Dynamic, Life-Sustaining Liquid Environments

A photograph of a polar bear in captivity, no matter how sharp the resolution, can never reveal as much about behavior as footage of that polar bear in its natural habitat. The behavior of cells and molecules can prove even more elusive…
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Metabolic Errors Affect DNA

Cells rely on purines, which are types of molecules that make up half of the DNA and RNA building blocks, and are a key component of the chemicals that store a cell’s energy in order to perform many vital functions. The purine supply is strictly controlled by the cells, with any disruption likely to cause […]

Scientists Transform Skin Cells Direct To Brain Cells, Bypassing Stem Cell Stage

Bypassing the stem cell stage, researchers at the Stanford University School of Medicine in California converted mouse skin cells directly into neural precursor cells, the cells that go on to form the three main types of cell in the brain and nervous system. They write about their findings in the 30 […]

Discovery Of Rotational Motion Of Cells That Plays A Critical Role In Their Normal Development Has Major Implications For Breast Cancer Research

In a study that holds major implications for breast cancer research as well as basic cell biology, scientists with the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab) have discovered a rotational motion that plays a critical role in the ability of breast cells to form the spherical structures in the mammary […]

Study Finds Mysterious Protein’s Entwined Arm Movements May Control Fate Of Potentially Toxic Payload

Like a magician employing sleight of hand, the protein mitoNEET - a mysterious but important player in diabetes, cancer and aging - draws the eye with a flurry of movement in one location while the subtle, more crucial action takes place somewhere else…
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Stress-Induced Genomic Instability Facilitates Rapid Cellular Adaption In Yeast

Cells trying to keep pace with constantly changing environmental conditions need to strike a fine balance between maintaining their genomic integrity and allowing enough genetic flexibility to adapt to inhospitable conditions…
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3D Study Of Vitamins May Help Combat Malaria

A three-dimensional study of how enzymes in the malaria parasite Plasmodium synthesize essential vitamins, could help develop new drugs to combat the disease. Using electron microscopy, a team of scientists from Germany and the UK studied how the enzymes synthesize Vitamin B6, which has already been proposed as a target for new drugs…
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One Of Life’s Molecular Mysteries Mapped By Scientists

All living organisms are made up of cells, behind these intricate life forms lie complex cellular processes that allow our bodies to function. Researchers working on protein secretion - a fundamental process in biology - have revealed how protein channels in the membrane are activated by special signals contained in proteins destined for secretion…
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Viruses That Con Bacteria With Helping Hand

Scientists studying ocean microorganisms have encountered something they have never seen before. A marine virus that cons certain photosynthetic bacteria into letting it come inside because it appears to offer a “helping hand” by bringing resources very like their own to help them acquire phosphorus, a nutrient they are desperately short […]


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