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Two projects by South Essex Partnership NHS Foundation Trust (SEPT) to promote dignity and independence for people who suffer from dementia were highly commended at this year’s East of England Health and Social Care Awards. The innovative projects ‘Lasting Memories’ and ‘My life Story’ were launched in December 2007 and work closely with patients, their carers, families and friends to improve their quality of life.

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Eisai Limited, the licence holder of Aricept(R) (donepezil hydrochloride) and Pfizer Limited, its co-promotion partner, welcomed today’s landmark ruling by the Court of Appeal. The Court found that the process by which the National Institute for Health and Clinical Excellence (NICE) decided to restrict anti-dementia medicines for newly diagnosed patients with mild Alzheimer’s disease was procedurally unfair.

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Alzheimer Scotland welcomes the recent findings from Professor Gordon Wilcock’s randomised phase II trial of tarenflurbil in patients with mild to moderate Alzheimer’s Disease, but cautions that the phase III stage will be crucial in ascertaining its true potential. The Oxford-based scientists, working with researchers across the world, found that there was a dose-related effect on measures of daily activities and function in patients with mild Alzheimer’s Disease.

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Alzheimer’s Society comment on new research suggesting tarenflurbil may be effective in halting symptoms of Alzheimer’s disease, from the Lancet Neurology. ‘This exciting clinical trial suggests a modification of a safe and readily available anti-inflammatory drug has a positive impact on memory and function for people with mild Alzheimer’s disease.

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Obesity may increase adults’ risk for having dementia, according to researchers at the Johns Hopkins Bloomberg School of Public Health. Their analysis of published obesity and dementia prospective follow-up studies over the past two decades shows a consistent relationship between the two diseases. The results are published by The International Association for the Study of Obesity in the May, 2008 issue of Obesity Reviews.

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In terms of the number of people affected, neurological diseases that contributed to decline in neuronal function are sometimes considered the newest healthcare epidemic. With the number of cases of neurodegenerative conditions expected to grow dramatically, driven by the aging population in developed countries, this therapeutic area represents one of the most compelling in both commercial and human terms.

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One in three people over 65 will die with dementia and too many of them are subjected to an undignified and unnecessarily painful death. This is often because staff lack the specialist training to provide good care at the end of someone’s life. It is vital that all people, not just those with cancer, benefit from good palliative care. The number of people living with dementia in the UK is set to soar to more than a million in less than twenty years.

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There is an urgent need to improve end-of-life care for older people in the final stages of dementia, according to an international review published in the May issue of Journal of Clinical Nursing. “We must act now to stop people with dementia from suffering from protracted, potentially uncomfortable and undignified deaths” says Jan Draper, Professor of Nursing for The Open University, UK.

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Researchers in the US studying a large patient population have shown that use of the anti-inflammatory and painkiller ibuprofen is linked to lower risk of developing Alzheimer’s disease. Patients who used the drug for more than 5 years were 40 per cent less likely to develop the disease compared with patients who did not use that type of drug at all.

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A study published in the May 1 issue of the journal SLEEP finds that sleep disturbances among Alzheimer patients vary significantly from those of their family caregivers, and that, surprisingly, poor sleep in either the patient or caregiver is not necessarily linked to disturbed sleep in the other.Susan M.

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