Structural Biology Scores With Protein Snapshot

In a landmark technical achievement, investigators in the Vanderbilt Center for Structural Biology have used nuclear magnetic resonance (NMR) methods to determine the structure of the largest membrane-spanning protein to date. Although NMR methods are routinely used to “take molecular pictures” of small proteins, large proteins - and particularly those that reside within the cell membrane - have been reluctant to smile for the camera.

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Filed under: Biology on June 27th, 2009