Shedding Light On The Mechanisms Of Early Stage Liver Reperfusion Injury

Reperfusion of a previously ischemic tissue is associated with additional injury leading to structural and functional alterations in many organs including the liver. The injury induced during reperfusion is has evolved into a biphasic pattern consisting of an early stage of reoxygenation and a delayed phase. It is thought that reactive oxygen species formation during reperfusion induces a cascade of a series of cellular events that eventually leads to hepatocellur injury.

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Filed under: GastroIntestinal / Gastroentorology on May 11th, 2009