News From The Journal Of Clinical Investigation, May 1, 2009

ONCOLOGY: How some immune cells improve cancer outcome For a number of cancers, including neuroblastoma (the second most common tumor in children), tumor infiltration by a subset of immune cells known as V-alpha-24-invariant NKT cells is associated with a favorable outcome. But how these cells have an anticancer effect is unclear, as many tumors do not express the protein that V-alpha-24-invariant NKT cells target.

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