Serum PSA Hemodilution Among Obese Men Undergoing Screening In The Prostate, Lung, Colorectal, And Ovarian Cancer Screening Trial

UroToday.com - This study reported in Cancer, Epidemiology, Biomarkers and Prevention used the same Prostate, Lung, Colorectal and Ovarian (PLCO) database as that by Andriole and colleagues in the NEJM article recently covered in Urotoday1. It is previously proposed that PSA levels in obese men could be due to hemodilution secondary to increased circulating blood volume. This study evaluated that phenomenon among 38,349 men randomized to the screened group of PLCO.

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