Revealing The Protein Effects Of Hormone Replacement Therapy

An in-depth proteomic analysis of the sera of 50 participants from the Women’s Health Initiative (WHI) hormone replacement therapy trial provides some explanations for the trial’s clinical results. The study, published in Biomed Central’s open access journal Genome Medicine, shows that estrogen upregulates proteins involved in several major body processes. Samir Hanash, M.D., Ph.D.

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