One Step Closer To A Treatment For Mixed-Lineage Leukemia

Infants and adults with the blood cancer mixed-lineage leukemia (MLL) typically have a poor prognosis, and most infants die before their first birthdays. Although there are varying causes of MLL, most cases are caused by a fusion of two genes, the MLL and the AF4 genes. When the MLL gene is fused to the AF4 gene, a potent cancer-causing oncogene is created.

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Filed under: Genetics on December 19th, 2008