Scientists Probe Limits Of “Cancer Stem-Cell Model”

One of the most promising new ideas about the causes of cancer, known as the cancer stem-cell model, must be reassessed because it is based largely on evidence from a laboratory test that is surprisingly flawed when applied to some cancers, University of Michigan researchers have concluded. By upgrading the lab test, the U-M scientists showed that melanoma—the deadliest form of skin cancer—does not follow the conventional cancer stem-cell model, as prior reports had suggested.

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Filed under: Cancer on December 4th, 2008