Molecular Partnership Controls Daily Rhythms, Body Metabolism

A research team led by Mitchell Lazar, MD, PhD, Director of the Institute for Diabetes, Obesity, and Metabolism at the University of Pennsylvania School of Medicine, has discovered a key molecular partnership that coordinates body rhythms and metabolism. Lazar and his colleagues, including the study’s first author Penn Veterinary Medicine doctoral student Theresa Alenghat, studied a protein called NCoR that modulates the body’s responses to metabolic hormones.

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