Master Gene Plays Key Role In Blood Sugar Levels

When mice that lack steroid receptor-2 (SRC-2) - a master regulator gene called a coactivator - fast for a day, their blood sugar levels plummet. If they go another day without food, they will die. The severity of the hypoglycemia (low blood sugar) was unexpected, said Dr. Bert W. O’Malley, chair of molecular and cellular biology at Baylor College of Medicine and senior author of the report on the study that appears in the current issue of the journal Science.

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