News From The Journal Of The National Cancer Institute, Oct. 28
Skewed X Inactivation in BRCA1 Mutation Carriers One X chromosome is more frequently silenced than the other X chromosome in women who carry mutations in the BRCA1 gene, and the skewed X inactivation is associated with a later onset of breast or ovarian cancer in these women. Each cell in a woman’s body carries two X chromosomes, while those of a man carry only one X chromosome.
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Filed under: Cancer on October 29th, 2008