Key To Sonic Hedgehog Control Of Brain Development Discovered By Penn Researchers

University of Pennsylvania School of Medicine researchers have discovered how the expression of the Sonic hedgehog gene is regulated during brain development and how mutations that alter this process cause brain malformations. The results appear online this month in Nature Genetics. Sonic hedgehog (Shh) plays a key role in regulating many aspects of embryonic development including, growth of digits on limbs and organization of neurons in the brain.

More: continued here

Filed under: Biology on October 29th, 2008