Rare Peptide Segments Are Found Significantly More Often In Proto-Oncoproteins Than Control Proteins: Implications For Immunology And Oncology

There is some evidence to suggest that peptide segments that are found rarely or never in the host proteome play a role in the immune response to disease-related proteins, both those derived from microbes and those derived from the host itself. We conjecture that this pattern may extend to human proto-oncoproteins.

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Filed under: Immune System / Vaccines on October 26th, 2008