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What Is The Pituitary Hormone Secretion Pattern In Cirrhosis Patients?

Hepatic encephalopathy, a major complication of cirrhosis, is a clinical syndrome characterized by mental status changes in patients with severe hepatic insufficiency. Hormonal disorders and circadian rhythm abnormalities are often associated with liver disease, and the severity of these disorders is related to liver disease severity and duration. The role of melatonin is critical, as diurnal melatonin rhythm disruption may significantly contribute to circadian function alterations.

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