Tracing Extensive Regulatory Networks That Help Determine How Certain RNA Messages Are Alternatively “Spliced”

Two professors at Cold Spring Harbor Laboratory (CSHL) have succeeded in tracing intricate biochemical networks involving a class of proteins that enable genes to express themselves in specific tissues at particular moments in development. Michael Q. Zhang, Ph.D. and Adrian R. Krainer, Ph.D., both professors at CSHL and heads of laboratories, are exploring a phenomenon that biologists and geneticists call RNA splicing.

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