Research Team Creates Human ALS Motor Neurons: First Disease-Specific Stem Cells From Human Skin Cells

A team of researchers from the Harvard Stem Cell Institute (HSCI) and Columbia University, in a collaboration catalyzed by the Project A.L.S./Jenifer Estess Laboratory for Stem Cell Research, has demonstrated that pluripotent stem cells generated from a patient with ALS (amyotrophic lateral sclerosis) can be directed to differentiate into motor neurons - the very brain cells destroyed by ALS. The results of the team’s study appear in the online issue of Science.

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