Pre-Power-Stroke Cross-Bridges Contribute To Force During Stretch Of Skeletal Muscle Myofibrils

When muscles are stretched while activated they produce large forces that cannot be readily explained by the current models of muscle contraction. The current experiments investigated the mechanisms behind stretch forces, and its association with the molecular basis of contraction. After performing experiments with sub-cellular muscle structures (i.e. myofibrils) it was concluded that muscle stretch changes the characteristics of muscle molecules while working to produce force.

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