Nucleostemin, Serotonin And Insulin Signaling: Controlling Drosophila Growth

In the July 15th issue of G&D, Dr. Matthew Scott and colleagues at Stanford University School of Medicine reveal that a protein called Nucleostemin 3 links the serotonin and insulin signaling pathways in the control of Drosophila body size. Nucleostemin proteins were originally identified in mammals, where they are associated with undifferentiated, proliferating stem cells. In human cells, Nucleostemin expression has been linked with certain types of cancer.

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Filed under: Biology on July 16th, 2008