Protein On ‘Speed’ Linked To ADHD

A genetic change in the dopamine transporter - one of the brain’s dopamine-handling proteins - makes it behave as if amphetamine is present and “run backward,” Vanderbilt University Medical Center investigators report this week in The Journal of Neuroscience. The altered function of the transporter gene variant, discovered in two brothers with attention deficit hyperactivity disorder (ADHD), supports a role for dopamine signaling in the disease.

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Filed under: ADHD on July 10th, 2008