Schizophrenia Linked To Dysfunction In Molecular Brain Pathway Activated By Marijuana

Alterations in a molecular brain pathway activated by marijuana may contribute to the cognitive symptoms of schizophrenia, according to a report in the July issue of Archives of General Psychiatry, one of the JAMA/Archives journals. Expression of the cannabinoid 1 receptor (CB1R), the site of action of the main chemical ingredient of marijuana, is significantly reduced in the brains of individuals with schizophrenia.

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Filed under: Alcohol / Addiction / Illegal Drugs on July 8th, 2008