News From The Journal Of The National Cancer Institute, June 10 2008
Novel Targeted Therapy Reduces Chemoresistance in Mouse Model of MelanomaA novel small molecule inhibitor reduced both endogenous and drug-induced resistance to chemotherapy in a mouse model of melanoma.The NF-κB pathway is often active in human cancers and promotes resistance to cytotoxic chemotherapy drugs. Some cytostatic drugs, such as doxorubicin, induce NF-κB pathway activity.
More: continued here
Filed under: Biology on June 11th, 2008