Risk Of Death And Stroke Increased By Use Of Metoprolol Around The Time Of Surgery: POISE Trial
May 15th 2008Drug InformationCardiovascular
Beta-blocker drugs may help prevent heart attacks during surgery, but they may increase the risk of death and major stroke, says a major study to be published online by the prestigious medical journal, The Lancet.POISE is the world’s largest randomized trial addressing perioperative cardiac complications. POISE evaluated the effects of a beta-blocker versus placebo given to patients around the time of surgery.
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