Does 1q31.1-32.1 Harbor A Tumor Suppressor Gene Related To Chinese SCC Patients?
May 15th 2008Drug InformationColorectal Cancer
The LOH analysis on sporadic carcinoma by means of microsatellite markers has become an effective way to find allelic deletion regions and then to find candidate tumor suppressor genes. In a previous study, it was found that D1S413 (1q31.1-32.1, 9.8cM) exhibited higher LOH frequencies, which indicated that the region might harbor the putative tumor suppressor gene(s).
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