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Curis Announces Genentech’s Initiation Of Hedgehog Antagonist Phase II Clinical Trial In Metastatic Colorectal Cancer

Curis, Inc. (NASDAQ: CRIS), a drug development company focused on developing the next generation of proprietary targeted medicines for cancer treatment, today announced that its collaborator Genentech has initiated a Phase II clinical trial of GDC-0449, an orally-administered small molecule Hedgehog antagonist, in metastatic colorectal cancer. As a result, Genentech will make a $3 million cash payment to Curis under the companies’ June 2003 collaboration agreement.

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