Ion Channel Disruption Causes Alteration Of Prefrontal Cortex Activity By Alcohol

* The prefrontal cortex (PFC) region of the brain is involved in decision making. * New rodent findings show that PFC neuron N-methyl-D-aspartic acid (NMDA) receptors are especially sensitive to concentrations of alcohol achieved during drinking. * This suggests that alcohol’s alteration of NMDA receptor function may inhibit normal PFC function.

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Filed under: Alcohol / Addiction / Illegal Drugs on April 4th, 2008