Identification Of First Sex Chromosome Gene Involved In Meiosis And Male Infertility

A team of scientists led by University of Pennsylvania veterinary researchers have identified a gene, TEX11, located on the X chromosome, which when disrupted in mice renders the males sterile and reduces female fecundity. This is the first study of the genetic causes of infertility that links a particular sex chromosome meiosis-specific gene to sterility.As with mice, the TEX11 gene is also located on the human X chromosome.

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Filed under: Fertility on April 2nd, 2008