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Breast Cancer Drug Tamoxifen May Decrease Mania Of Bipolar Disorder

The drug tamoxifen is usually used to treat breast cancer, butresearchers say that it also may reduce symptoms of mania in peoplewith bipolar disorder. An article summarizing the small, three-weektrial of tamoxifen is published in Archives of GeneralPsychiatry.As a treatment for breast cancer, tamoxifen impacts the way in whichthe hormone estrogen works in the body. In addition, tamoxifen worksagainst the actions of the protein kinase C family of enzymes.

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