Increased Oxidative Stress In Decompensated Cirrhotic Patients

Oxidative stress describes the state level of oxidative damage in a cell, tissue or organ, caused by reactive oxygen species. Alcohol induces oxidative stress in the liver resulting in an imbalance between oxidants and anti-oxidants. Increased reactive oxygen species (ROS) production and glutathione (GSH) depletion, lead to abnormal breakdown of fat molecules (i.e., lipid peroxidation).

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Filed under: Alcohol / Addiction / Illegal Drugs on February 26th, 2008