ASCO GU 2008 - Prostate Stem Cell Insight Into Tumor Initiation

UroToday.com - John Isaacs, Johns Hopkins discussed stem cell biology. Cancer is caused by a series of genetic changes (both germ line and somatic). Genetic instability can occur even in cancer cells, influencing their behavior. He cited the Gleason scoring system as an example of phenotypic heterogeneity.

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