ASCO GU 2008 - Correlating Androgen Levels And Steroidogenic Enzyme Expression In Castration-Resistant Prostate Cancer (CRPC) Metastases

UroToday.com - Dr. Mostaghel reviewed the potential sources of tissue androgens from the androgen metabolic pathway. This includes the uptake and conversion of circulating adrenal androgens, and the de novo androgen biosynthesis of androgens from cholesterol, progesterone or earlier precursors.Tumor tissue was obtained from the warm autopsy study at the University of Washington.

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Filed under: Endocrinology on February 18th, 2008