Medication Response In Patients With Alcohol Dependence Predicted By Gene Variant

Patients with a certain gene variant drank less and experienced better overall clinical outcomes than patients without the variant while taking the medication naltrexone, according to an analysis of participants in the National Institutes of Health’s 2001-2004 COMBINE (Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence) Study. About 87 percent of patients with the variant who received naltrexone.

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Filed under: Alcohol / Addiction / Illegal Drugs on February 8th, 2008