Gene Dose Affects Tumor Growth

Researchers at Johns Hopkins and Ohio State University have found that the number of copies of a particular gene can affect the severity of colon cancer in a mouse model. Publishing in the Jan. 3 issue of Nature, the research team describes how trisomy 21, or Down syndrome in humans, can repress tumor growth. “We took a new approach to a 50-year-old debate about whether people with Down syndrome develop cancer less often than other people,” says Roger H. Reeves, Ph.

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Filed under: Cancer on January 6th, 2008