AD, Omega-3 Fatty Acids, And A Lipoprotein Receptor

This is one of those good-fat-bad-fat stories for your holiday reading. Ma et al. examined the lipid regulation of an ApoE/low-density lipoprotein receptor, the neuronal sortilin-related receptor (SorLA or LR11). LR11 can reduce â-amyloid production by guiding APP in recycling Golgi and early endosome pathways, thus trafficking APP away from â- and ã-secretase. [click link for full article]

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