Genomic Instability, Human RecQ Helicases And Homologous Recombination

Two independent papers in the December 1st issue of G&D detail how human RecQ helicases regulate homologous recombination and protect genome stability.The human RecQ family of helicases consists of 5 members: WRN, BLM, RECQL4, RECQL1 and RECQL5. These enzymes help to unwind DNA so to facilitate replication, transcription and DNA repair. [click link for full article]

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Filed under: Cancer on November 18th, 2007